Table 2.

Clinical adverse events

Adverse eventGrade255075100100*125*175*
Fatigue23111101
3-40000003
Anemia21130003
3-42000010
Nausea20111003
3-41110010
Vomiting21012001
3-40110010
Diarrhea20010000
3-41000000
Headache20201001
3-40100000
Anorexia22001011
3-40000001
Reduced LVEF20011000
3-40000000
Hypertension20000100
3-40000100
Pulmonary embolism20000000
3-40000020
Troponin I increase20000000
3-40000010
ALP elevation20000012
3-40000012
  • Abbreviation: ALP, alkaline phosphatase.

  • * Continuous schedule.