Table 4.

Relevant pharmacokinetic parameters of MG98 (mean ± SD) in all treated patients

ParameterDose level 1 (n = 8)Dose level 2 (n = 7)Dose level 3 (n = 7)
Cmax (μg/mL)34.0 ± 9.5760.5 ± 14.5
Tmax (h)1.9 ± 0.11.8 ± 0
Css (μg/mL)0.462 ± 0.3620.720 ± 0.3091.07 ± 0.531
t1/2 (h)1.2 ± 0.51.0 ± 0.21.7 ± 0.4