Multivariate Cox proportional hazards analysis of MGI in entire cohort
| Variable | Hazard ratio (95% confidence interval) | P | |
|---|---|---|---|
| MGI | High vs low | 4.7 (2.1-10.8) | 0.0002 |
| Tumor size | >2 cm vs <2 cm | 0.8 (0.4-1.5) | 0.4580 |
| Tumor grade | 0.0011 | ||
| II vs I | 1.6 (0.5-5.2) | 0.4331 | |
| III vs I | 5.6 (1.5-20.6) | 0.0105 | |
| Age | ≥35 y vs <35 y | 0.7 (0.2-1.9) | 0.4687 |
| Node status | Pos. vs neg. | 1.2 (0.6-2.3) | 0.5581 |
| Treatment | 0.5733 | ||
| Chemo vs none | 0.9 (0.4-2.4) | 0.8837 | |
| Endo vs none | 1.5 (0.5-4.5) | 0.4406 | |
| Chemo + endo vs none | 1.0 (0.3-3.5) | 0.9939 |
Abbreviations: Pos, positive; Neg, negative; Chemo, chemoteraphy; Endo, endocrine therapy.