Table 3.

Correlation of tuberin phosphorylation with AKT activation

Tuberin P-S939 positiveTuberin P-S939 negative
AKT (active) P-S473-positive167
AKT (inactive) P-S473-negative411
  • NOTE: Phosphorylation of tuberin at S939 was significantly associated with the presence of active AKT (phospho-S473) as determined by Cohen's κ statistic (0.415; 95% confidence interval, 0.127-0.702).