Table 1.

Baseline patient characteristics (n = 55)

Age, y, median (range)61 (31-84)
Gender, male/female38 (69%):17 (31%)
Current diagnosis, n (%)
    Cohort 1
        AML23 (42%)
        MDS2 (4%)
        CML (nonlymphoid blast crisis)1 (2%)
    Cohort 2
        ALL1 (2%)
    Cohort 3
        AMM9 (16%)
    Cohort 4
        CLL8 (15%)
    Cohort 5
        T-cell leukemia/lymphoma2 (4%)
        MCL9 (16%)
ECOG-PS* 0, 1, 2; n (%)14 (26%), 33 (61%), 7 (13%)
No. prior chemotherapies
    07
    13
    213
    315
    45
    57
    63
    ≥72
  • Abbreviation: ECOG-PS, Eastern Cooperative Oncology Group Performance Status.

  • * n = 54.