Table 1.

Effect of motesanib treatment on breast cancer cell proliferation in vitro

IC50 (nmol/L)Breast cancer cell line
MCF-7 (luminal)MDA-MB-231 (mesenchymal)Cal-51 (mixed/progenitor)
Motesanib>3,000>3,000>3,000
Docetaxel0.50.50.6