Table 1.

Evaluation of rNAPc2 in modulating tumor burden in small intestine in ApcMin/+ mice

Microscopic measurementsApcMin/+ mice
Saline controlrNAPc2
Tumor no.23.1 ± 7.5 (100)10.5 ± 2.7* (46)
Tumor size (mm)0.59 ± 0.09 (100)0.48 ± 0.05* (80)
Total tumor area (mm2)7.73 ± 0.89 (100)2.54 ± 0.49* (33)
% of Adenoma79.6 ± 3.289.7 ± 4.2*
% of Adenocarcinoma20.4 ± 3.210.3 ± 4.2*
  • NOTE: Percentage data (in parentheses) are arbitrarily normalized to saline control.

  • * P < 0.05 (rNAPc2 versus saline control). Mean ± SD (n = 6 mice per group).