Table 1.

Significantly enriched gene ontology terms (P < 0.01) for genes up-regulated (P < 0.01) in reactive stroma

Category/termPFold
Neurogenesis
    Dendrite development0.000311.7
    Neurite development0.002410.5
    Neural crest cell migration0.00817
    Axonogenesis0.00085.4
    Synapse organization and biogenesis0.00235.3
    Neurite morphogenesis0.00134.9
    Cell soma0.00884.8
    Synaptic transmission0.00962.2
DNA damage and repair
    DNA damage checkpoint0.00685.2
    DNA damage response, signal transduction0.00154.8
    DNA integrity checkpoint0.01004.7
    Response to DNA damage stimulus0.00582
Morphogenesis and development
    Cell part morphogenesis0.00134.9
    Cell projection morphogenesis0.00134.9
    Cell projection organization and biogenesis0.00214.5
    Epidermis development0.00253.4
    Cellular structure morphogenesis0.00153.1
Metabolic processes
    Cellular polysaccharide catabolic process0.00538.1
    Polysaccharide catabolic process0.00538.1
    Oxidoreductase activity, acting on CH-OH group of donors0.00982.7
    Monocarboxylic acid metabolic process0.00092.5
    Fatty acid metabolic process0.00452.5
    Regulation of hydrolase activity0.00632.4
Kinase activity
    Calmodulin-regulated protein kinase activity0.00986.6
    Protein kinase cascade0.00352.6
    Protein serine/threonine kinase activity0.00162
Membrane and ion transport
    Chloride transport0.00804
    Porter activity0.00892.2
    Electrochemical potential–driven transporter activity0.00922.2
    Carrier activity0.00532
Transcription regulation
    Positive regulation of transcription from RNA pol II promoter0.00512.6
Apoptosis
    DNA fragmentation during apoptosis0.00667.5
    Cell structure disassembly during apoptosis0.00187.4