Table 1.

Drugs affecting PPARγ signaling

AgentReceptorDrug classFood and Drug Administration approved
PioglitazonePPARγThiazolidinedioneYes
RosiglitazonePPARγThiazolidinedioneYes
CiglitazonePPARγThiazolidinedioneNo
TroglitazonePPARγThiazolidinedioneYes/withdrawn
FarglitizarPPARγThiazolidinedioneNo
MuraglitizarPPARα,γThiazolidinedioneNo
GW7845PPARγUnknownNo
GW7875PPARγUnknownNo
GW501516PPARδUnknownNo
LG10068RXRαRetinoidNo
ClofibratePPARαFibrateYes
Prostaglandin J2PPARγProstaglandinNo