Table 3.

Overall response to vorinostat and bortezomib

Prior BortezomibNo of Pts (n = 23)Response
VGPRPRSDPDNE
Naïve4121
Pretreatment1012511
Refractory93411
Pts treated at MTD, n = 11)
Naïve22
Pretreatment321
Refractory624

Abbreviations: Pts, patients; VGPR, very good PR; NE, not evaluable.