Table 1.

Patient characteristics

DiagnosisNo. casesPrior Tx, range (median)*
Peritoneal mesothelioma51-3 (2)
Pleural mesothelioma90-4 (2)
Pleural-peritoneal mesothelioma21-3 (2)
Ovarian cancer72-9 (6)
Pancreatic carcinoma11
Total240-9 (2)
Dose levels of SS1PNo. enrolledNo. patients with DLT
4 μg/kg/d ×1030
8 μg/kg/d ×10 (3)30
12 μg/kg/d ×10 (3)61
18 μg/kg/d ×10 (3)60
25 μg/kg/d ×10 (3)61
Ages: 31-69, median 60
Males: 13, females: 11
  • *Number of prior chemotherapy regimens per patient.