Multivariate analyses of factors associated with OS and RFS (n = 314)
| Variables | OS | RFS | ||
|---|---|---|---|---|
| Hazard ratio (95% confidence interval) | P | Hazard ratio (95% confidence interval) | P | |
| γ-Glutamyl transferase, units/L (>54 vs ≤54) | 1.70 (1.26-2.29) | <0.001 | 1.49 (1.10-2.03) | 0.011 |
| Tumor differentiation (III-IV vs I-II) | 1.31 (0.96-1.80) | 0.088 | NA | |
| Tumor encapsulation (none vs complete) | 1.27 (0.94-1.71) | 0.117 | NA | |
| Tumor size, cm (>5 vs ≤5) | 1.14 (0.84-1.56) | 0.390 | NA | |
| Tumor number (multiple vs single) | 1.42 (0.98-2.07) | 0.063 | 1.41 (0.95-2.11) | 0.090 |
| Vascular invasion (yes vs no) | 1.80 (1.24-2.63) | 0.002 | 1.78 (1.18-2.68) | 0.006 |
| Satellite (yes vs no) | 2.30 (1.45-3.67) | <0.001 | NA | |
| CD24 (positive vs negative) | 1.82 (1.35-2.45) | 0.0001 | 2.55 (1.88-3.47) | <0.0001 |
NOTE: Cox proportional hazards regression model. The clinicopathologic variables were adopted for their prognostic significance by univariate analyses.
Abbreviation: NA, not applicable.