Table 2.

Multivariate overall survival and colorectal cancer–specific survival analysis for colorectal cancer cases based on ODC1 genotype

ODC1 GenotypeP
GGGA/AA
Overall mortality
    Number of events4762
    Number at risk208192
    Unadjusted HR (95% CI)1 (reference)1.57 (1.07-2.29)0.020
    Adjusted HR (95% CI)*1 (reference)1.58 (1.07-2.34)0.021
CRC-specific mortality
    Number of events2237
    Number at risk208192
    Unadjusted HR (95% CI)1 (reference)1.97 (1.16-3.34)0.012
    Adjusted HR (95% CI)*1 (reference)2.02 (1.17-3.50)0.012

Abbreviation: 95% CI, 95% confidence interval.

  • *Includes stratification for stage (I, II, III) and adjustment for age (y), gender, ethnicity, family history of colorectal cancer, TNM stage at diagnosis, tumor site within the colorectum, histologic subtype, treatment with surgery, radiation therapy, and chemotherapy.