Table 6.

Changes of PBMC histone acetylation after treatments

Patient IDTumor typePhenylbutyrate dose level, (mg/m2/d)/DHistone acetylation
H3H4
11RectalA-2 (400)/D6, D13
12RenalB1 (200)/D8 to D14+
13Colon
14ProstateA-3 (400)/D6, D13
15Prostate
16Breast
17MesotheliaB2 (400)/D8 to D14
19Bladder+
21Renal++
24ColonC1 (400)/D6, D13, D20++
31RectalC2 (400)/D6, D13, D20+
32Colon++
33Lung++

NOTE: −, no changes; +, increase; D, days.