Table 2.

Change in ambulatory blood pressure measurements in sorafenib patients

VariableBL (n = 54)Day 1 (n = 25)Days 6-10 (n = 54)Weeks 5-7 (n = 44)Change in BP (days 6-10 - BL; n = 54)Change in BP (day 1 - BL; n = 25)
SBP (mm Hg)
    Mean120.8129.1131.6131.610.88.2
    SD10.411.312.111.68.17.6
    Median118.9124.8131.1131.19.47.0
    Range 97.9 to 143.3112.5 to 148.2108.8 to 158.2103.1 to 155.5−5.2 to 28.7−7.2 to 23.9
    95% CI8.6-13.05.0-11.3
    P<0.0001<0.0001
DBP (mm Hg)
    Mean71.376.679.280.08.06.5
    SD7.07.18.18.06.24.5
    Median71.976.879.8817.35.8
    Range 53.1 to 89.359.7 to 88.663.4 to 98.762.9 to 98.2−4.4 to +27.1−0.7 to 16.7
    95% CI6.3-9.74.7-8.3
    P<0.0001<0.0001

Abbreviations: BL, baseline; BP, blood pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure.