Table 2.

Correlations of B7-H1 and B7-DC with tumor-infiltrating epithelial T cells

Intraepithelial infiltrationCategory*n (%)B7-H1, n (%)B7-DC, n (%)
NegativePositivePNegativePositiveP
CD8+Low34 (34)31 (91)3 (9)0.16223 (68)11 (32)0.824
High66 (66)52 (79)14 (21)46 (70)20 (30)
CD4+Low46 (46)42 (91)4 (9)0.06031 (75)15 (25)0.829
High54 (54)41 (76)13 (24)38 (70)16 (30)
Foxp3+Low38 (41)36 (95)2 (5)0.02227 (71)11 (29)1.000
High55 (59)42 (76)13 (24)38 (69)17 (31)
CD8+/Treg ratioLow49 (54)40 (82)9 (18)0.77833 (67)16 (33)0.820
High42 (46)36 (86)6 (14)30 (71)12 (29)
CD4+/Foxp3 ratioLow47 (52)37 (79)10 (21)0.26330 (64)17 (36)0.266
High44 (48)39 (89)5 (11)33 (75)11 (25)
CD8+/CD4+ ratioLow51 (51)43 (70)8 (30)0.79438 (75)13 (25)0.281
High49 (49)40 (82)9 (18)31 (63)18 (37)

Abbreviation: Treg, regulatory T cell.

  • *The patients were divided in two categories with low or high numbers of infiltrating cells (or ratio between subtype of cells) based on the 50th percentile.