Table 3.

PD-1 expression on TILs

Cell typeMedian cell number per mm2 (min-max)
B7-H1–positive tumorB7-H1–negative tumorP
CD8+ T cells198 (48-505)160 (9.7-314)0.337
CD4+ T cells114 (4.8-317)73 (15-190)0.170
Foxp3+ T cells81 (30-219)53 (16-101)0.138
CD8+PD-1- T cells47.5 (7.5-439)61 (6.1-101)0.529
CD8+PD-1+ T cells107.2 (14-252)85 (1.2-208)0.462
CD8+Foxp3+ T cells3.7 (1.1-5.8)2.3 (0.0-11)0.713
CD8+PD-1+Foxp3+ T cells2.2 (0.0-24)2.4 (0.0-7.1)0.815
CD4+PD-1+ T cells56.1 (2.4-193)16.2 (2.1-138)0.248
CD4+Foxp3+ T cells47.0 (0.0-169)42.2 (5.8-78)0.345
CD4+PD-1+Foxp3+ T cells25.3 (2.4-47)7.7 (3.7-20)0.074