Table 2.

Top 20 genes differentially expressed in tumors from patients with reduced relapse-free survival in study 1 (unadjusted analysis)

GeneFold change between relapsers and nonrelapsersHazard ratio (95% confidence interval)Significance value
OSTEOPONTIN1.553.17 (1.91-5.26)2.11 × 10−6
RAD54B1.398.59 (3.17-23.31)9.40 × 10−6
HMMR1.434.36 (2.08-9.13)0.00006
CDKN2B0.710.33 (0.19-0.56)0.0001
DEK1.1516.94 (4.32-66.45)0.0001
TK11.237.82 (2.70-22.65)0.0002
ITGB40.740.35 (0.20-0.60)0.0002
BIRC51.304.36 (1.82-10.41)0.0003
DSP0.650.60 (0.46-0.78)0.0003
ING11.1312.81 (3.07-53.47)0.0003
TOP2A1.196.86 (2.19-21.49)0.0003
AR0.630.25 (0.11-0.55)0.0003
E2F51.343.86 (1.82-8.19)0.0004
TGFA0.660.32 (0.16-0.63)0.0004
RECQL1.188.64 (2.58-29.00)0.0004
BLM1.244.35 (1.86-10.14)0.0005
FHIT1.263.99 (1.75-9.10)0.0006
GRB70.660.53 (0.37-0.76)0.0006
TFAP2C0.750.36 (0.20-0.64)0.0006
RAD511.304.16 (1.81-9.53)0.0007