Derivation of irRC overall responses
Measurable response | Nonmeasurable response | Overall response | |
---|---|---|---|
Index and new, measurable lesions (tumor burden),* % | Non-index lesions | New, nonmeasurable lesions | Using irRC |
↓100 | Absent | Absent | irCR† |
↓100 | Stable | Any | irPR† |
↓100 | Unequivocal progression | Any | irPR† |
↓≥50 | Absent/Stable | Any | irPR† |
↓≥50 | Unequivocal progression | Any | irPR† |
↓<50 to <25↑ | Absent/Stable | Any | irSD |
↓<50 to <25↑ | Unequivocal progression | Any | irSD |
≥25? | Any | Any | irPD† |