Table 5.

Best prior response and time to progression for current responders

Cohort no.Patient no.Prior treatment regimen(s)Best prior response153Sm-lexidronam (mCi/kg)Bortezomib (mg/m2)Response to 153Sm-lexidronam/bortezomibTime to progression (mo)
209Doxorubicin/vincristine/dexamethasoneCR0.51.0CR4.1
318Melphalan/prednisoneSD1.01.0CR7.2
Thalidomide
406Doxorubicin/vincristine/dexamethasoneSD1.01.3CR7.1
512ThalidomidePR0.251.3MR8.3
Thalidomide/methylprednisolone
Melphalan/bortezomib
620Melphalan/bortezomibMR0.51.3MR6.4
  • Abbreviations: CR, complete response; PR, partial response; MR, minimal response; SD, stable disease.