Error rates | PFS Rates at a given time point (with equivalent hazard ratios Δ) | |||
---|---|---|---|---|

20% vs. 35% (1.53) | 20% vs. 40% (1.76) | 40% vs. 55% (1.53) | 40% vs. 60% (1.79) | |

(α,β) = (10%,10%) | 256 | 156 | 316 | 182 |

(α,β) = (10%,20%) or (20%,10%) | 184 | 112 | 224 | 132 |

(α,β) = (20%,20%) | 126 | 78 | 150 | 90 |

NOTE: Calculations were carried out using nQueryAdvisor 5.0 software (Statistical Solutions) based on methods given in Fleiss et al. (27) with one-sided α.