Table 1.

Multivariate Cox regression analysis of miR-451 expression and DFS in gastric cancer patients

A. Multivariate analysis of postoperative DFS of 21 patients in stage III gastric carcinoma treated with adjuvant chemoradiotherapy in relation to stage, miR-451, and hsa-miR-126 expression normalized by the median or RNAU6B (control). miRNA expression was categorized as low or high in relation to median values
VariableSubsetHR (95% CI)P
Data of miRNA expression normalized by median (stage III)
StageIIIA/IIIB½.5 (0.72-9.14)0.148
miR-451Low/High4.78 (1.2-18.5)/10.025
miR-126Low/High2.56 (0.76-9.6)/10.122
Data of miRNA expression normalized by U6B snRNA (stage III)
StageIIIA/IIIB½.7 (0.8-9.3)0.103
miR-451Low/High4.74 (1.3-17.3)/10.001
B. Multivariate analysis of postoperative DFS of 45 patients with gastric carcinoma (stages I-IV) treated with adjuvant chemoradiotherapy in relation to stage and miR-451 expression
Variable
Subset
HR (95% CI)
P
StageI+II/III+IV1/6 (1.7-21.2)0.005
miR-451Low/High3.7 (1.5-8.7)/10.003
  • Abbreviations: HR, hazards ratio; 95% CI, 95% confidence interval; snRNA, small nuclear RNA.