Table 2.

Tagging efficiency of genes evaluated

GeneSize (kb)SNP data sourceNo. common variants MAF > 0.05No. tagSNPs selected for r2 > 0.8*No. (%) common variants tagged r2 > 0.8 (pairwise)No. (%) common variants tagged r2 > 0.5No. (%) SNPs tagged with r2s > 0.8No. common variants tagged by multimarker tags with r2s > 0.8
PTGS124.7Seattle SNPs39635 (90)38 (97)35 (90)NIL
PTGS28.6Seattle SNPs18714 (78)15 (83)14 (78)NIL
PTGES14.7HapMap16514 (88)15 (94)15 (94)NIL
PTGIS64.3HapMap411638 (93)38 (93)38 (93)NIL
PTGDS10.7HapMap18317 (94)18 (100)18 (100)1
PGDS44.3HapMap1029 (90)9 (90)9 (90)NIL
TBXAS1241.9HapMap1482579 (53)109 (74)100 (68)7
  • Abbreviations: r2, pairwise correlation coefficient; r2s, correlation between a SNP and haplotype.

  • * Successfully assayed.

  • See Supplementary Table S2.