Table 1.

Clinicopathologic characteristics for the metastatic and nonmetastatic cohorts

Metastatic (n = 30)Nonmetastatic (n = 30)P
Age at diagnosis (y), mean (range)53.1 (29-88)52.6 (30-81)NS
Tumor grade, n (%)
    Moderate12 (40)12 (40)NS
    Poor18 (60)18 (60)NS
Tumor size (cm), mean (range)3.5 (1-11)3.7 (1-10)NS
Lymph node metastasis, present, n (%)20 (67)19 (63)NS
No. lymph nodes positive, mean (range)4.7 (0-17)4.3 (0-14)NS
Lymphovascular invasion, present, n (%)18 (60)11 (37)NS
Hormone status, n (%)
    Estrogen receptor-positive19 (63)18 (60)NS
    Progesterone receptor-positive11 (37)15 (50)NS
HER-2/neu overexpression, present, n (%)9 (30)7 (23)NS
  • NOTE: A search of the Cancer Registry database of the New York-Presbyterian Hospital/Weill Cornell Medical Center from 1992 to 2003 yielded 30 patients with known metastatic disease who had undergone primary resection of their breast cancer at New York-Presbyterian Hospital. The same database was then searched to identify a matched nonmetastatic control for each metastatic case. The controls were matched for each of the parameters listed above. There was a minimum follow-up time of 5 y for all cases, and the follow-up time for each control was at least as long as the follow-up time for its metastatic pair.

    Abbreviation: NS, not significant; P > 0.05.