Table 1.

Characteristics of prostate cancer cases and controls in study of aggressive disease

Cases (n = 466)Controls (n = 478)
Age (y), mean ± SD65.5 ± 8.165.7 ± 8.2
Ethnicity, n (%)
    African American76 (16.3)481 (17.0)
    Caucasian390 (83.7)397 (83.0)
Family history of prostate cancer, n (%)
    Negative438 (94.0)473 (98.9)
    Positive*28 (6.0)5 (1.1)
Smoking (pack-years), n (%)
    Never194 (41.7)189 (39.9)
    ≤1088 (18.9)90 (19.0)
    10-2051 (11.0)62 (13.1)
    20-4085 (18.3)81 (17.1)
    ≥4047 (10.1)52 (10.9)
Body mass index (kg/m2), mean ± SD27.7 ± 4.627.9 ± 4.7
Prior history of PSA test, n (%)
    Never99 (22.3)104 (23.9)
    Once54 (12.1)66 (15.2)
    Twice or more292 (65.6)265 (60.9)
Serum PSA value (ng/mL), mean ± SD13.5 ± 23.31.7 ± 1.7
Clinical stage, n (%)
    T1c285 (64.0)
    Any T2133 (29.9)
    T327 (6.1)
Histologic tumor grade: Gleason score, n (%)
    ≤675 (16.1)
    7287 (61.6)
    ≥8104 (22.3)
  • * Family history of prostate cancer was defined as two or more first-degree relative per family or one first-degree and two or more second-degree relatives.

  • Numbers do not always add to 100% because of missing data.