Table 3.

Tolerance of treatment

A. Reason for treatment cessation
HACA12
Protocol completion*4 (1 with 2 cycles)
Disease progression13
Toxicity3
B. Cycle 1 toxicities (grade 3/4)
Treatment Level12345678910
Leukopenia122122
Lymphopenia231221
Platelet111
Rash111
Anemia2
  • * The protocol had included two cycles of treatment but was amended to allow up to three cycles.

  • Grade 2.