Table 3.

Distribution of mutations throughout the response groups

Mutation
Best response
n (row %)CRPRSDPDTotal
KRAS WT/PI3K WT1 (0.9)31 (29)55 (51)21 (19)108 (100)
KRAS WT/PI3K mutant05 (36)8 (57)1 (7)14 (100)
KRAS mutant/PI3K WT01 (1)42 (62)25 (37)68 (100)
KRAS mutant/PI3K mutant007 (78)2 (22)9 (100)
Total1 (0.5)37 (19)112 (56)49 (25)199* (100)
  • NOTE: %, distribution of responses in each mutation group.

    Abbreviations: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.

  • * KRAS data were not available for one of the patients.