Distribution of mutations throughout the response groups
| Mutation | Best response | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| n (row %) | CR | PR | SD | PD | Total | ||||
| KRAS WT/PI3K WT | 1 (0.9) | 31 (29) | 55 (51) | 21 (19) | 108 (100) | ||||
| KRAS WT/PI3K mutant | 0 | 5 (36) | 8 (57) | 1 (7) | 14 (100) | ||||
| KRAS mutant/PI3K WT | 0 | 1 (1) | 42 (62) | 25 (37) | 68 (100) | ||||
| KRAS mutant/PI3K mutant | 0 | 0 | 7 (78) | 2 (22) | 9 (100) | ||||
| Total | 1 (0.5) | 37 (19) | 112 (56) | 49 (25) | 199* (100) | ||||
NOTE: %, distribution of responses in each mutation group.
Abbreviations: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.
↵* KRAS data were not available for one of the patients.