Comparison of clinical and tumor pathology factors between identified two MINT locus clusters in all patients
| MINT3 and MINT17 | P | ||
|---|---|---|---|
| Clusters 1, 2, and 4 | Cluster 3 | ||
| n = 184 | n = 67 | ||
| Sex, n (%) | |||
| Male | 116 (72) | 46 (28) | 0.41 |
| Female | 68 (76) | 21 (24) | |
| Age (y) | |||
| Mean (SE) | 62.7 (0.9) | 65.0 (1.4) | 0.17 |
| TNM stage, n (%) | |||
| I | 51 (73) | 19 (27) | 0.78 |
| II | 57 (76) | 18 (24) | |
| III | 76 (72) | 30 (28) | |
| N status, n (%) | |||
| N0 (≥12 examined) | 27 (79) | 7 (21) | 0.67 |
| N0/NX (<12 examined) | 82 (73) | 30 (27) | |
| N1 (1-3 positive) | 44 (72) | 17 (28) | |
| N2 (≥4 positive) | 32 (73) | 12 (27) | |
| Differentiation, n (%) | |||
| Well | 14 (78) | 4 (22) | 0.90 |
| Moderately | 128 (73) | 48 (27) | |
| Poor | 42 (74) | 15 (26) | |
| Location distant recurrences, n (%) | |||
| Liver | 19 (70) | 8 (30) | 0.44 |
| Nonliver | 24 (59) | 17 (41) | |
| Resection type, n (%) | |||
| Low anterior | 125 (75) | 42 (25) | 0.46 |
| Abdominoperineal | 53 (69) | 24 (31) | |
| Hartmann | 6 (86) | 1 (14) | |
| Circumferential margin, n (%) | |||
| Negative | 152 (73) | 55 (27) | 1 |
| Positive | 32 (73) | 12 (27) | |