Table 2.

Multivariate analyses in all analyzed patients

VariableLocal Recurrence
HR (95% CI)P
T stage (III-IV)1.16 (0.44-3.08)0.76
Node (+)3.40 (1.39-8.33)0.007
Circumferential margin (+)2.27 (0.93-5.53)0.07
Distance from anal verge <5 cm 1.40 (0.62-3.18)0.42
Poor differentiation0.98 (0.40-2.41)0.96
MINT locus profile*10.23 (1.38-75.91)0.02

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.

  • *“Cluster 3” is null-hypothesis.