Table 1.

Summary of immunostaining results of DNMT3L for primary TGCTs and malignant lymphomas of the testis

Tumor TypeNo. of DNMT3L-positive cases (%)Total no. of cases
TGCTs of adolescents
    Pure seminomas0 (0%)30
    Nonseminomatous TGCTs21 (91.3%)23
    Foci of nonseminomatous TGCTs
    EC21 (100%)*21†
    Seminoma0 (0%)7
    Teratoma0 (0%)9‡
    Yolk sac tumor0 (0%)12†
TGCTs of infants
    Teratoma0 (0%)2
    Yolk sac tumor0 (0%)1
Malignant lymphomas of the testis0 (0%)5

  • ↵*P < 0.0001 embryonal carcinoma versus nonembryonal carcinoma.

  • ↵†Foci of embryonal carcinoma include six pure embryonal carinomas; foci of yolk sac tumor includes one pure yolk sac tumor.

  • ↵‡Foci of teratoma include four immature teratomas.