Table 1.

χ2 and P values for xenograft studies

PLD vs IL-PLD dose-response study (Fig. 3)χ2P
Ctrl vs 8 mg/kg PLD single dose0.14540.7029
Ctrl vs 12 mg/kg PLD single dose2.4960.1141
Ctrl vs 16 mg/kg PLD single dose7.5040.0062
Ctrl vs 8 mg/kg 3 doses3.6460.0562
Ctrl vs 8 mg/kg IL-PLD single dose4.7950.0285
Ctrl vs 12 mg/kg IL-PLD single dose4.9220.0265
Ctrl vs 16 mg/kg IL-PLD single dose7.5040.0062
Ctrl vs 8 mg/kg IL-PLD 3 doses7.5040.0062
PLD vs 8 mg/kg IL-PLD single dose6.80.0091
PLD vs 12 mg/kg IL-PLD single dose0.72420.3948
PLD vs 16 mg/kg IL-PLD single dose0.024250.8762
PLD vs 8 mg/kg IL-PLD 3 doses7.3440.0067
8 mg/kg PLD single dose vs 8 mg/kg PLD 3 doses4.7950.0285
8 mg/kg IL-PLD single dose vs 8 mg/kg IL-PLD 3 doses4.2680.0388
PLD vs IL-PLD vs IL-null study (Fig. 4)χ2P
Ctrl vs PLD20.5<0.0001
Ctrl vs IL-PLD26.5<0.0001
Ctrl vs PLD + free HB22.710.790.001
Ctrl vs IL-null11.480.0007
IL-PLD vs PLD12.940.0003
IL-PLD vs PLD + free HB22.714.870.0001
IL-PLD vs IL-null9.8240.0017
PLD vs PLD + free HB22.70.30520.5806
PLD vs IL-null0.080970.776
IL-null vs PLD + free HB22.70.15590.693

NOTE: Data were analyzed using the modified Kaplan- Meier curves and the Log-rank test as described in Materials and Methods. Comparisons with significant P values (<0.05) are shown in bold.

Abbreviation: Ctrl, control.