Table 2.

Tumor characteristics and PET parameters by subtype

CharacteristicsTN (n = 25)HER2 (n = 6)Luminal n = 40P global difference by subtype*Odds ratio, P TN vs luminal
Tumor grade
    3 (vs 1 or 2)22 (88%)4 (67%)18 (45%)8.7
    95% CI§(70%, 96%)(30%, 90%)(31%, 60%)0.001<0.001
Ki-67 proliferative index
    High (vs low or intermediate)20 (95%)3 (60%)22 (63%)0.0111.4
    95% CI§(77%, 100%)(23%, 88%)(46%, 77%)0.009
PCR
    pCR (vs no or partial response) 7 (28%)4 (67%)5 (13%)0.0142.7
    95% CI§(14%, 48%)(30%, 90%)(5%, 26%)0.188
MRFDG, μmol/min/100 g
    Mean15.97.589.720.0090.019
    SD10.45.317.8
BF, mL/min/g
    Mean0.3540.3150.3520.7310.773
    SD0.1480.1290.214
MRFDG: BF ratio
    Mean44.324.128.70.0040.011
    SD2314.614.6
  • *Fisher's exact test for grade, Ki-67, pCR; likelihood ratio test for PET.

  • Odds ratio and Fisher's exact test P value for grade, Ki-67, and pCR; Tukey-Kramer test for PET (difference not given for log-transformed variables).

  • Five luminal tumors were grade 1; others were grade 2.

  • §CIs computed using Wilson (score) method.

  • Missing values, n = 4 (TN), n = 1 (Her2), and n = 5 (luminal).