Tumor characteristics and PET parameters by subtype
| Characteristics | TN (n = 25) | HER2 (n = 6) | Luminal n = 40 | P global difference by subtype* | Odds ratio, P TN vs luminal† |
|---|---|---|---|---|---|
| Tumor grade | |||||
| 3 (vs 1 or 2)‡ | 22 (88%) | 4 (67%) | 18 (45%) | 8.7 | |
| 95% CI§ | (70%, 96%) | (30%, 90%) | (31%, 60%) | 0.001 | <0.001 |
| Ki-67 proliferative index∥ | |||||
| High (vs low or intermediate) | 20 (95%) | 3 (60%) | 22 (63%) | 0.01 | 11.4 |
| 95% CI§ | (77%, 100%) | (23%, 88%) | (46%, 77%) | 0.009 | |
| PCR | |||||
| pCR (vs no or partial response) | 7 (28%) | 4 (67%) | 5 (13%) | 0.014 | 2.7 |
| 95% CI§ | (14%, 48%) | (30%, 90%) | (5%, 26%) | 0.188 | |
| MRFDG, μmol/min/100 g | |||||
| Mean | 15.9 | 7.58 | 9.72 | 0.009 | 0.019 |
| SD | 10.4 | 5.31 | 7.8 | ||
| BF, mL/min/g | |||||
| Mean | 0.354 | 0.315 | 0.352 | 0.731 | 0.773 |
| SD | 0.148 | 0.129 | 0.214 | ||
| MRFDG: BF ratio | |||||
| Mean | 44.3 | 24.1 | 28.7 | 0.004 | 0.011 |
| SD | 23 | 14.6 | 14.6 | ||
↵*Fisher's exact test for grade, Ki-67, pCR; likelihood ratio test for PET.
↵†Odds ratio and Fisher's exact test P value for grade, Ki-67, and pCR; Tukey-Kramer test for PET (difference not given for log-transformed variables).
↵‡Five luminal tumors were grade 1; others were grade 2.
↵§CIs computed using Wilson (score) method.
↵∥Missing values, n = 4 (TN), n = 1 (Her2), and n = 5 (luminal).