Table 2.

RTL, TRF1, TRF2, and the expression of DDR proteins during bronchioloalveolar carcinogenesis

Histology (no. of cases studied)RTL mean scoreTRF1 mean scores ± SDTRF2 mean scores ± SDp-ATM mean scores ± SDp-H2AX mean scores ±SDp-CHK2 mean scores ±SD
Normal PII-bronchiolar cells23050101010
AAH (n = 27)1.874 ± 3787 ± 6348 ± 4255 ± 46113 ± 47
AIS (n = 6)1.3375 ± 5100 ± 3576 ± 5556 ± 4483 ± 56
Stage I-II ADC (n = 18)285 ± 62123 ± 51125 ± 72124 ± 8697 ± 51
Stage III-IV ADC (n = 6)1.83101 ± 43115 ± 5296 ± 5367 ± 4655 ± 56