Table 1.

Patient characteristics

CharacteristicsBIBF 1120
Once dailyTwice daily
No. of patients2536
Gender
    Male (n)1531
    Female (n)105
Age59 (41-74)63 (34-83)
    Median (range)
ECOG performance status at baseline
    079
    11726
    211
Prior therapy
    Surgery2333
    Chemotherapy2429
    Radiotherapy915
    Immunotherapy*58
    Hormonal therapy14
Tumor type
    Colorectal1416
    Kidney, ureter19
    Pleura32
    Prostate03
    Breast20
    Sarcoma, soft tissue11
    Head and neck02
    Lung02
    Pancreas10
    Liver, biliary tree20
    Cervix, vagina and vulva10
    Thyroid01

Abbreviation: ECOG, Eastern Cooperative Oncology Group.

  • *Immunotherapy comprised, e.g., IFN, interleukin, levamisole.