Table 2.

Methylation of candidate genes in the evaluation set

KIf1aNISCHRarBDCCB4GALT1
Controls1/24 (4%)2/24 (8%)1/24 (4%)0/11 (0%)2/10 (20%)
Cancers3/11 (27%)4/11 (36%)5/13 (38%)6/11 (54%)1/9 (11%)
P = 0.08P = 0.06P = 0.01P = 0.01P = 1

NOTE: The plasma samples from the evaluation set were tested for methylation of five candidate tumor suppressor genes, (RarB, NISCH, B4GALT1, KIF1a, and DCC). Kif1a, DCC, RarB, and NISCH showed differences in methylation status that seemed to be associated with cancer.