Table 1.

JAK2-dependent and JAK2-independent gene sets

NameAffymetrix IDLog ratio (normal/PV)PEntrez gene ID
A. JAK2-dependent PV signature genes*
    AIM1212543_at2.60.021202
    ANXA5200782_at2.30.0424308
    BACH2221234_s_at3.70.000760468
    BCL6203140_at3.90.0003604
    BLNK207655_s_at4.3029760
    GALNAC4S-6ST203066_at3.70.000951363
    HLA-DMB203932_at2.50.02573109
    IRF8204057_at4.603394
    KLF4221841_s_at2.20.04859314
    LOC100133941266_s_at30.007100133941
    LY86205859_at2.40.0369450
    PLAC8219014_at3.40.002351316
    RNASE6213566_at2.50.02336039
    TIPARP212665_at2.50.025325976
B. JAK2-independent PV signature genes
    DEFA1205033_s_at−2.301667
    MCL1214057_at1.50.00014170
    P2RY14206637_at1.709934
    C13orf15218723_s_at2028984
    INHBC207688_s_at1.60.00013626
    SAMHD1204502_at1.40.000325939
    ARL4C202207_at1.50.000210123
    TGFB1201506_at1.507045
    DEFA4207269_at−1.601669
    ILF2200052_s_at1.10.01643608
    SNRPE215450_at1.40.00066635
    YBX1208627_s_at1.20.0064904
  • *A set of 14 genes common in the PV and cell line data sets, which distinguish normal specimens and PV with high efficiency.

  • A set of 12 genes derived from the PV expression signature, from which JAK2 regulated genes were subtracted, which distinguish normal specimens and PV with high efficiency.