Table 1.

Characteristics of females and matched males with SCCHN

VariableFemales (n = 286), n(%)Males (n = 286), n (%)P
Age* category, y0.788
    <5076 (26.6)69 (24.1)
    50-69172 (60.1)179 (62.6)
    ≥7038 (13.3)38 (13.3)
Race/ethnicity*1.0
    White, Anglo, Caucasian264 (92.3)264 (92.3)
    Spanish origin10 (3.5)10 (3.5)
    African American12 (7.7)12 (7.7)
Adult comorbidity classification0.078
    None or mild257 (89.9)243 (85.0)
    Moderate or severe29 (10.1)43 (15.0)
Smoking status*0.980
    Current smoker140 (49.0)142 (49.7)
    Former smoker75 (26.2)73 (25.5)
    Never smoker71 (24.8)71 (24.8)
Alcohol drinking status<0.001
    Current drinker110 (38.5)162 (56.6)
    Former drinker50 (17.5)71 (24.8)
    Never drinker126 (44.1)53 (18.5)
Marital status0.002
    Married185 (66.6)215 (77.9)
    Widowed, divorced, or separated81 (29.1)46 (16.7)
    Never married12 (4.3)15 (5.4)
Educational level attained0.840
    <High school37 (13.3)34 (12.4)
    High school, technical or vocational school, or associate degree or some college161 (57.9)166 (60.3)
    Bachelor's degree or advanced degree80 (28.8)75 (27.3)
Income level0.281
    <$25,00075 (27.8)59 (22.0)
    $25,000-74,999112 (41.5)116 (43.3)
    ≥$75,00083 (30.7)93 (34.7)
Tumor site*1.0
    Oral cavity132 (46.2)132 (46.2)
        Oral tongue or floor of mouth8888
        Gingivobuccal4444
    Oropharynx92 (32.2)92 (32.2)
        Tonsil4843
        Other oropharynx4449
    Larynx55 (19.2)55 (19.2)
        Supraglottic4334
        Glottic1221
    Hypopharynx7 (2.4)7 (2.4)
Tumor classification*0.992
    T177 (26.9)74 (25.9)
    T2104 (36.4)107 (37.4)
    T355 (19.2)55 (19.2)
    T450 (17.5)50 (17.5)
Nodal classification*0.247
    N0140 (49.0)140 (49.0)
    N149 (17.1)34 (11.9)
    N289 (31.1)105 (36.7)
    N38 (2.8)7 (2.4)
Stage0.621
    I56 (19.6)54 (18.9)
    II54 (18.9)56 (19.6)
    III55 (19.2)44 (15.4)
    IV121 (42.3)132 (46.2)
Grade§0.995
    Well differentiated34 (11.9)34 (11.9)
    Moderately differentiated140 (49.0)141 (49.3)
    Poorly differentiated76 (26.6)75 (26.2)
Treatment*1.0
    Surgery alone85 (29.7)85 (29.7)
    Surgery + radiotherapy45 (15.7)45 (15.7)
    Surgery + chemotherapy1 (0.3)1 (0.3)
    Surgery + chemoradiotherapy21 (7.3)21 (7.3)
    Radiotherapy alone64 (22.4)64 (22.4)
    Chemoradiotherapy70 (24.5)70 (24.5)
  • *Matched variables (age, ±10 y; race/ethnicity; smoking status, ever versus never; tumor site, oral cavity versus oropharynx versus larynx versus hypopharynx; tumor classification, T1-2 versus T3-4; nodal classification, N0 versus N1-3; and treatment).

  • Missing data: 8 women and 10 men for marital status; 8 women and 11 men for education level attained; and 16 women and 18 men for income level.

  • One female and the corresponding matched male had a primary tumor of the mandibular gingiva and a simultaneous second primary tumor of the oropharynx.

  • §Grade was not recorded in 36 females and 36 males.