Table 2.

Extramedullary toxicity

ToxicityDose level
18.5 MBq/kg (n = 3)27.75 MBq/kg (n = 3)37 MBq/kg (n = 21)46.25 MBq/kg (n = 4)
Bilirubin
    Grade 30031
    Grade 40010
Alkaline phosphatase (grade 3)0010
AST/ALT (grade 3)0010
Creatinine (grade 3)0010
Infusion-related reaction (grade 3)0010
GI bleeding (grade 4)0010

Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; GI, gastrointestinal.