Table 1.

Patients and primary tumor characteristics by CTC and M30-positive CTC count

A)
Breast cancer patientsnCTC negativeCTC positiveP*M30+P*M30+ %P
All subjects3415 (44%)19 (56%)15 (79%)53.9
Age at diagnosis, y≤350
36-5012480.477165.1
≥51221111845.8
SexM101100.210
F3315181556.9
T (n = 19)T114950.4250.1869.50.54
T24221100
T31011100
T40
N (n = 20)N0127514174.41
N1-N3844468.8
M (n = 17)M04221211000.14
M+1385452
Grading (n = 18)G15410.4010.38500.018
G2523232.5
G38444100
Estrogen receptors (n = 20)-74312166.71
+1376549.6
Progestin receptors (n = 20)-10460.365166.31
+1073233.3
Her2 (n = 20)-191180.457152.81
+101150
B)
Colorectal cancer patientsnCTC negativeCTC positiveP*M30+P*M30+ %P
All subjects5933 (56%)26 (44%)24 (92.3%)84
Age at diagnosis, y≤3510111187.5
36-5053]2]2]]100
≥515330232182
SexM3822161160.13887
F211110879
T (n = 47)Tis10640.12830.347750.671
T0330
T14222100
T2945595
T317116692
T4404477
N (n = 47)N03722150.687140.936880.303
N1624497
N2211120
Nx2111100
M (n = 47)M04125160.075151841
M1615598
C)
Renal cancer patientsnCTC negativeCTC positiveP*M30+P*M30+ %P
All subjects2910 (34.5%)19 (65.5%)17 (89.5%)78
Age at diagnosis, y≤35321110.1167
36-50303283
≥5123815490
SexM239140.8412184
F615596
T (n = 19)T14130.5730.63780.47
T2321180
T31147567
T41011100
N (n = 19)N09450.6450.46891
N1-N31037562
M (n = 11)M05230.8120.45560.45
M12111100
Mx413389
Fuhrman grading (n = 15)G1
G2413131891
G31156574
Histology (n = 27)CC carcinoma228141130.33840.08
Others523238
Sites of metastasis at blood draw (n = 25)Contralateral kidney4400.026
Lung, mediastinal LN or liver123970.68640.28
Bone936694

Abbreviations: T, tumor; N, node; M, metastasis; LN, lymph node.

  • *Fisher' exact test or χ2 (‡) test were employed where appropriate.

  • Median test.

  • χ2 test.