Table 2.

Functional annotations of the 63 genes identified as differentially expressed among the 2 NMF groups by SAM 2-class analysis

Probe set IDGene symbolGene titleScore (d)Fold changeq (%)Cytoband
212869_x_atTPT1Tumor protein, translationally controlled 1−6.33080.79013q12–q14
209009_atESDEsterase D/formylglutathione hydrolase−5.01300.56013q14.1–q14.2
215136_s_atEXOSC8Exosome component 8−4.58880.612.1913q13.1
222182_s_atCNOT2CCR4-NOT transcription complex, subunit 2−4.49110.692.1912q15
202723_s_atFOXO1Forkhead box O1−4.39060.673.2613q14.1
205134_s_atNUFIP1Nuclear fragile X mental retardation protein interacting protein 1−4.32570.663.2613q14
210346_s_atCLK4CDC-like kinase 4−4.31460.653.265q35
213256_atMARCH3Membrane-associated ring finger (C3HC4) 3−4.16960.514.205q23.2
203597_s_atWBP4WW domain binding protein 4 (formin binding protein 21)−4.12580.644.2013q14.11
204155_s_atQSKSerine/threonine-protein kinase QSK−4.06620.724.7211q23.3
213011_s_atTPI1Triosephosphate isomerase 13.93551.604.7212p13
201013_s_atPAICSPhosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase3.94071.734.724q12
204047_s_atPHACTR2Phosphatase and actin regulator 23.94281.334.726q24.2
201850_atCAPGCapping protein (actin filament), gelsolin-like3.94392.244.722p11.2
201577_atNME1Nonmetastatic cells 1, protein (NM23A) expressed in3.96021.624.7217q21.3
217865_atRNF130Ring finger protein 1303.96172.024.725q35.3
203857_s_atPDIA5Protein disulfide isomerase family A, member 53.99101.254.013q21.1
201105_atLGALS1Lectin, galactoside-binding, soluble, 13.99673.274.0122q13.1
40489_atATN1Atrophin 14.03881.234.0112p13.31
44120_atADCK2aarF domain containing kinase 24.06161.184.017q32–q34
209329_x_atHIGD2AHIG1 hypoxia inducible domain family, member 2A4.06861.274.015q35.2
40850_atFKBP8FK506 binding protein 8, 38kDa4.07681.354.0119p12
203507_atCD68CD68 molecule4.08091.224.0117p13
201605_x_atCNN2Calponin 24.10171.594.0119p13.3
211793_s_atABI2Abl-interactor 24.10521.264.012q33
217806_s_atPOLDIP2Polymerase (DNA-directed), delta interacting protein 24.13881.263.2617q11.2
221269_s_atSH3BGRL3SH3 domain binding glutamic acid-rich protein like 34.19761.583.261p35–p34.3
211622_s_atARF3ADP-ribosylation factor 34.20201.253.2612q13
217457_s_atRAP1GDS1RAP1, GTP-GDP dissociation stimulator 14.22391.261.954q23–q25
204875_s_atGMDSGDP-mannose 4,6-dehydratase4.24551.631.956p25
217736_s_atEIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 14.27281.571.957p22
205770_atGSRGlutathione reductase4.28001.351.958p21.1
207722_s_atBTBD2BTB (POZ) domain containing 24.30071.501.9519p13.3
206200_s_atANXA11Annexin A114.30521.621.9510q23
208877_atPAK2p21 protein (Cdc42/Rac)-activated kinase 24.34491.841.953q29
212566_atMAP4Microtubule-associated protein 44.36081.501.953p21
200788_s_atPEA15Phosphoprotein enriched in astrocytes 154.38381.571.951q21.1
219162_s_atMRPL11Mitochondrial ribosomal protein L114.42121.291.9511q13.3
217211_at4.44141.411.95
32209_atFAM89BFamily with sequence similarity 89, member B4.46151.701.9511q23
212330_atTFDP1Transcription factor Dp-14.50851.951.9513q34
202041_s_atFIBPFibroblast growth factor (acidic) intracellular binding protein4.51751.711.9511q13.1
208677_s_atBSGBasigin (Ok blood group)4.55871.781.9519p13.3
200001_atCAPNS1Calpain, small subunit 14.61761.71019q13.12
218037_atFAM134AFamily with sequence similarity 134, member A4.70821.4802q35
37965_atPARVBParvin, beta4.78961.48022q13.2–q13.33
213739_at4.81741.280
221059_s_atCOTL1Coactosin-like 1 (Dictyostelium)4.85242.20016q24.1
211672_s_atARPC4 /// TTLL3Actin-related protein 2/3 complex, subunit 4, 20kDa /// tubulin tyrosine ligase-like family, member 34.90821.6803p25.3
200838_atCTSBCathepsin B5.09361.5808p22
201426_s_atVIMVimentin5.12721.82010p13
213453_x_atGAPDHGlyceraldehyde-3-phosphate5.29861.70012p13
214119_s_atFKBP1AFK506 binding protein 1A, 12kDa5.32261.78020p13
209041_s_atUBE2G2Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)5.38331.65021q22.3
201251_atPKM2Pyruvate kinase, muscle5.41681.92015q22
208829_atTAPBPTAP binding protein (tapasin)5.52711.5506p21.3
201082_s_atDCTN1Dynactin 1 (p150, glued homolog, Drosophila)5.53972.0902p13
218388_atPGLS6-Phosphogluconolactonase5.88841.89019p13.2
201516_atSRMSpermidine synthase5.90121.5701p36–p22
201136_atPLP2Proteolipid protein 2 (colonic epithelium-enriched)6.04221.620Xp11.23
200966_x_atALDOAAldolase A, fructose-bisphosphate6.10411.72016p11.2
203683_s_atVEGFBVascular endothelial growth factor B6.33301.51011q13
208308_s_atGPIGlucose phosphate isomerase7.12611.94019q13.1