Time-stratified hazard ratios, breast cancer–specific mortality adjusted for race, age at diagnosis, and date of diagnosis
| Breast cancer–specific, time-stratified HR (95% CI) | ||
|---|---|---|
| Years 0–5 | Years > 5 | |
| Race | ||
| White | 1.00 | 1.00 |
| African American | 1.6 (1.2–2.3) | 1.9 (1.2–3.0) |
| Menopause | ||
| Premenopausal | 1.00 | |
| Postmenopausal | 0.8 (0.6–1.1)a | |
| Subtypes | ||
| Luminal A | 1.00 | 1.00 |
| Luminal B | 1.3 (0.7–2.5) | 1.5 (0.8–2.8) |
| Basal | 2.7 (1.8–4.0) | 0.6 (0.3–1.3) |
| HER2+/ER− | 2.9 (1.7–5.0) | 1.6 (0.8–3.5) |
| Unclassified | 1.9 (1.2–3.2) | 0.8 (0.3–1.8) |
| Combined subtypes | ||
| Luminal A and B | 1.00 | 1.00 |
| Basal | 2.5 (1.7–3.7) | 0.6 (0.3–1.1) |
| HER2+/ER− | 2.8 (1.6–4.6) | 1.5 (0.7–3.2) |
| ER status | ||
| ER+ | 1.00 | 1.00 |
| ER− | 2.5 (1.8–3.5) | 0.7 (0.4–1.1) |
| PR status | ||
| PR+ | 1.00 | 1.00 |
| PR− | 2.2 (1.6–3.1) | 1.0 (0.6–1.6) |
| HER2 status | ||
| HER2− | 1.00 | |
| HER2+ | 1.4 (1.0–1.8)a | |
↵aSingle estimate given because proportional hazards assumption was not violated.