Axillary lymph node variables stratified by tumor size, according to breast tumor subtype
| Basal-like | Luminal A | Luminal B | HER2+/ER− | Unclassified | |
|---|---|---|---|---|---|
| (n = 199) | (n = 608) | (n = 111) | (n = 69) | (n = 132) | |
| Lymph node status, % positive tumors (n) | |||||
| ≤2 cm | 30 (70) | 19 (329) | 35 (57) | 23 (22) | 21 (63) |
| >2–5 cm | 41 (106) | 54 (228) | 61 (44) | 59 (37) | 47 (51) |
| >5 cm | 57 (21) | 79 (48) | 86 (7) | 100 (10) | 56 (18) |
| P valuea | 0.07 | <0.0001 | 0.004 | 0.0002 | 0.002 |
| Number of positive lymph nodes, mean (median) | |||||
| ≤2 cm | 1.4 (0) | 0.7 (0) | 1.4 (0) | 0.5 (0) | 1.3 (0) |
| >2–5 cm | 1.8 (0) | 2.2 (1.0) | 3.1 (1.0) | 3.2 (1.0) | 2.5 (0) |
| >5 cm | 4.0 (1.0) | 5.4 (2.0) | 7.6 (4.0) | 6.3 (6.0) | 4.1 (1.0) |
| P valueb | 0.04 | <0.0001 | 0.001 | <0.0001 | 0.002 |
| % positive lymph nodes, mean (median) | |||||
| ≤2 cm | 13% (0) | 5% (0) | 13% (0) | 5% (0) | 10% (0) |
| >2–5 cm | 14% (0) | 19% (7%) | 19% (10%) | 19% (11%) | 22% (4%) |
| >5 cm | 24% (8%) | 34% (18%) | 46% (54%) | 47% (42%) | 29% (7%) |
| P valueb | 0.17 | <0.0001 | 0.005 | <0.0001 | 0.007 |