Table 4.

MORAb-009 pharmacokineticsa

MORAb-009 (mg/m2)Mean Cmax (μg/mL)Mean AUC(0–168) (μg·h/mL)Mean t1/2 (h)
Day 1Day 22Day 1Day 22Day 1Day 22
12.5752967835878
2543b600b37b
5024381,9034,97191247
10053774,1656,7138268
20011918710,42422,57093236
40024452121,52872,65696244
  • aPharmacokinetic values after the first (day 1) and fourth (day 22) dose of MORAb-009.

  • bData not available because only 1 out of 3 patients treated at this dose level had blood drawn for C1D22 pharmacokinetic analysis.