Table 3.

Detection of gold nanoparticles in normal and neoplastic tissues from subjects treated with various doses of CYT-6091

Dose, μg/m2Patient IDDiagnosisSite of biopsyNormal tissueTumor tissue
ParticlesFieldsParticlesFields
50 0601-01 Cutaneous melanomaChest Wall1010916
0601-02 Colon adenocarcinomaLiver261311
0601-03 Ocular melanomaLiver04511
100 0601-04 Colon adenocarcinomaLiver051310
0601-05 Colon adenocarcinomaND
0601-06 Ocular melanomaScalp1707
150 0601-07 Lung adenocarcinomaLiver06335
0601-08 Pancreatic adenocarcinomaLiver0613512
0601-09 Pancreatic adenocarcinomaLiver2505
200 0601-10 Invasive ductal carcinomaBreast051675
0601-11 LeiomyosarcomaMuscle343110
0601-12 Ocular melanomaLiver76810
250 0601-13 Ocular melanomaMuscle19704
0601-15 Pancreatic adenocarcinomaLiver1547
0601-16 Ocular melanomaLiver0505
300 0601-17 Colon adenocarcinomaND
0601-18 Ocular melanomaLiver8101612
0601-19 Ocular melanomaLiver15655
0601-20 Ocular melanomaLiver23606
400 0601-21 Desmoplastic small round cellOmentum0506
0601-22 Rectal adenocarcinomaLiver277105
0601-23 Colorectal adenocarcinomaLiver78605
500 0601-24 Ocular melanomaSkin0819
0601-25 Invasive ductal carcinomaLiver148907
0601-26 Colorectal adenocarcinomaND
600 0601-27 Desmoplastic small round cellND
0601-28 Colorectal adenocarcinomaND
0601-29 Colorectal adenocarcinomaND
0601-30 AdenocarcinomaND

Abbreviation: ND, not determined.