Table 3.

Univariate and multivariate logistic regression results including clinical and genomic score variables

VariablesUnivariate analysisMultivariate analysis
OR (95% CI)POR (95% CI)P
Age, y1.01 (0.95-1.06)0.820.98 (0.90-1.06)0.61
Prechemotherapy T size (2-4 vs 0-1)0.68 (0.13-3.54)0.640.85 (0.06-12.14)0.91
Clinical N stage (N1-3 vs N0)6.17 (0.77-49.41)0.0872.99 (0.28-31.40)0.36
Nuclear grade5.06 (1.44-17.80)0.0111.97 (0.34-11.49)0.45
ER status (positive vs negative)0.07 (0.02-0.34)0.000910.20 (0.02-1.87)0.16
HER-2 status (positive vs negative)9.94 (1.96-50.42)0.00564.45 (0.52-38.14)0.17
Clinical nomogram score1.49 (1.16-1.90)0.00160.98 (0.64-1.49)0.91
DLDA30 score1.52 (1.13-2.04)0.00551.29 (0.69-2.39)0.42
In vivo T/FAC COXEN GEM score1.40 (1.03-1.90)0.0341.05 (0.50-2.20)0.90
In vitro T/FAC COXEN GEM score0.95 (0.81-1.13)0.590.83 (0.63-1.90)0.18

NOTE: OR, ORs for having pCR versus RD. ER status was determined by immunohistochemistry and HER2 status was determined by immunohistochemistry or fluorescence in situ hybridization. Predictor scores, age, and nuclear grade were used as continuous variables.