Table 1.

Patient characteristics

CharacteristicPatients with high MSH2Patients with low MSH2All patients (n = 673)P*
tumors (n = 257)tumors (n = 416)
NumberPercentNumberPercentNumberPercent
Sex0.05
    Male221863267854781
    Female3614902212619
Age0.99
    <55 years70271273119729
    55-64 years116451814429744
    >64 years71281082617927
Pathological TNM stage0.79
    Stage I83321503623335
    Stage II53211022515523
    Stage III121471643928542
Tumor0.83
    T1361463159915
    T2145562636340861
    T37429822015623
    T42182101
Nodes0.99
    N0122471884531046
    N169271253019429
    N266261032516925
Histological type0.002
    Adenocarcinoma51201543720530
    Squamous-cell carcinoma174682175239158
    Other NSCLC321245117711
Surgery0.34
    Pneumonectomy118461613927941
    Lobectomy or segmentectomy139542556139459
Performance status scored0.37
    0147572225336955
    184331654024937
    22610297558
Lymphoid infiltration0.20
    Not intense235913608759588
    Intense22956137812
Pleural invasion0.19
    No232903869361892
    Yes2510307558
Vascular invasion0.44
    No181702957147671
    Yes76301212919729
Lymphatic invasion0.19
    No71281373320831
    Yes186722796746569
Quality after H&E staining0.01
    Average37142876510
    Good220863889360890

NOTE: Percentages may not total 100 because of rounding.

  • *P values testing the difference between positive and negative tumors were calculated using logistic regression stratified on centre.

  • TNM denotes tumor-node-metastases.

  • World Health Organization scores.