Table 4.

Stratified analysis of rs5742714 genotypes associated with NSCLC patients survival

Variablesrs5742714 (deaths/patients)Adjusted HR (95% CI)*Heterogeneity P
CCCG/GG
Smoking0.173
    Nonsmokers75/13830/550.98 (0.63-1.53)
    Smokers144/23952/1150.67 (0.49-0.93)
Histology0.729
    Adenocarcinoma137/23748/1000.77 (0.55-1.08)
    Squamous cell69/12027/590.75 (0.48-1.18)
    Others13/207/111.25 (0.38-4.15)
Stage0.535
    Early stage (I-II)52/13818/670.68 (0.39-1.18)
    Late stage (III-IV)167/23964/1030.83 (0.61-1.11)
Surgical operation0.045
    None107/13945/570.99 (0.69-1.42)
    Yes112/23837/1130.58 (0.40-0.85)
Chemotherapy or radiotherapy0.356
    None31/7214/311.01 (0.51-2.03)
    Yes188/30568/1390.71 (0.53-0.94)
  • *Adjusted for age, sex, smoking, histology, stage, surgical operation and chemotherapy or radiotherapy status.

  • Other carcinomas include large cell, undifferentiated and mixed-cell carcinomas.