Table 1.

Baseline characteristics of all randomized patients

Placebo/placebo (n = 22)Celex/placebo (n = 23)Exem/placebo (n = 22)Exem/celex (n = 23)
Median age (range)62 (54-75)60 (53-78)62 (53-79)64 (50-84)
Grade I14% (3)13% (3)5% (1)0% (0)
    II27% (6)30% (7)36% (8)52% (12)
    III59% (13)52% (12)55% (12)48% (11)
Invasive cancer52% (12)44% (10)50% (11)35% (8)
Median tumor size (range)15 (5-100)23 (9-60)27 (1-68)17 (1-80)
PR positive68% (15)78% (18)71% (15)68% (15)
HER2 positive (3+)32% (7)26% (6)36% (8)35% (8)
COX-2 positive (3+)62% (13)59% (13)45% (9)64% (14)

NOTE: All patients took 14 d of study drugs in the 14 d immediately preceding surgery.

Abbreviation: Exem, exemestane.