Table 1.

Correlations between Pak1 cytoplasmic expression, Pak1 nuclear expression, pERser305, and clinicopathologic parameters in postmenopausal breast carcinomas

Pak1 nuclear expressionPak1 cytoplasmic expressionpERser305 nuclear expression
n (%)n (%)n (%)
+P+P+P
Total615 (78)171 (22)333 (42)453 (58)536 (64)305 (36)
Tamoxifen
    −294 (78)81 (22)0.92149 (40)226 (60)0.15257 (63)148 (37)0.87
    +321 (78)90 (22)184 (45)227 (55)279 (64)157 (36)
Tumor size
    ≤20mm451 (75)149 (25)<0.001277 (46)323 (54)<0.001389 (61)253 (39)<0.001
    >20mm149 (90)17 (10)46 (28)120 (72)134 (75)45 (25)
ER status
    −144 (86)24 (14)0.0157 (34)111 (66)0.009131 (72)51 (28)0.008
    +458 (77)138 (23)270 (45)326 (55)390 (61)246 (39)
PR status
    −279 (83)56 (17)0.02139 (41)196 (59)0.59243 (68)113 (32)0.07
    +281 (76)87 (24)160 (43)208 (57)240 (62)148 (38)
pERser305
    −384 (80)99 (20)0.46178 (37)305 (63)0.001
    +203 (77)60 (23)129 (49)134 (51)