Table 1.

Patient characteristics and relations to markers

Characteristic or markerTotalHPV16p16Bcl2BclXL
+P*+P*+P*+P*
Age<60 y447370.136380.3227170.6026180.80
≥60 y248166181771311
GenderFemale10281190.68910.085550.73
Male581345114735233424
SiteTonsil356290.0484310.0262213121140.67
Tongue base2962352419101514
Other431313131
T stage118117<0.0011170.0031260.636120.083
23333033019142112
31064558282
4752345243
N stage07520.012430.049610.20520.71
11129298356
24673964026202719
3413044022
StageII1010.45010.28010.12100.87
III1551051012387
IV52104274532203022
Smoking<1 pack-year33132<0.0011320.00318150.1317160.46
≥1 pack-year35142111242692213
ExcessiveNo53647<0.001449<0.0013419129240.56
Alcohol useYes159687105105
HPV16Negative15123<0.0011230.23961
Positive5305332213023
p16Negative12930.52751
Positive5635213224
Bcl2Negative4425191
Positive241410
BclXLNegative39
Positive29
  • *Fisher exact test; P < 0.05 highlighted in bold.